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Interaction Proteome
Interaction Proteome
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4th Annual Report
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Executive Summary 2007
Majorca Presentations
Annual Meeting 2007: NEW DATE and LOCATION
HUPO 2006 Poster Prize
Annual Meeting Majorca 2006 completed
Annual Meeting 2006: Programme & Hotel Reservation
FP7
Annual Report: Executive Summary
Scientific Advisory Board established
Partners
Beatson Institute
for Cancer Research
Glasgow, UK
EMBL,
Heidelberg, D
GSF-National Research
Centre for Environment
and Health,
Neuherberg, D
JPT Peptide Technologies,
Berlin, D
FEI Company,
Eindhoven, NL
ThermoElectron GmbH, Bremen, D
Max Planck Institute
of Biochemistry
Martinsried, Germany
Technical University of Denmark,
Copenhagen, DK
Flanders Interuniversity Institute of Biotechnology
University Tor Vergata,
Rome, I
University of Southern Denmark,
Odense, DK
Press Information
Third Annual Report: Executive Summary
In the press: A Showcase Project for EU Research
Second Annual Report: Executive summary
First Annual Report: Executive Summary
In the press: Interaction Proteome
In the press: Electron Microscopy Network 3D-EM gets EU-Framework Support
In the press: Cryo-Electron Tomography in the Era of Structural Proteomics
In the press: BIOSpektrum Special "Proteomics" 09/2004
Press Release European Commission, April 6, 2004
Project start
European Pharmaceutical Review 2006
Second Annual Report: Executive Summary
Publications
Top-down quantitation and characterization of SILAC-labeled proteins
Gender-enriched transcription of activation associated secreted proteins in Ostertagia ostertagi
Identification and characterization of a novel specific secreted protein family for selected members of the subfamily Ostertagiinae (Nematoda)
The minimum information required for reporting a molecular interaction experiment (MIMIx)
High-precision FLIM-FRET in fixed and living cells reveals heterogeneity in a simple CFP-YFP fusion protein
Vaccination against Ostertagia ostertagi with subfractions of the protective ES-thiol fraction
Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling
Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation
Genome-wide proteomics of Natronomonas pharaonis
Proteolytic cleavage of the Chlamydia pneumoniae major outer membrane protein in the absence of Pmp10
PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites
A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes
A new approach for mapping sialylated N-glycosites in serum proteomes
Genome-wide proteomics of Natronomonas pharaonis
Higher-energy C-trap dissociation for peptide modification analysis
Identification of nascent chain interaction sites on trigger factor
ProtNet: a tool for stochastic simulations of protein interaction networks dynamics
WI-PHI: a weighted yeast interactome enriched for direct physical interactions
MINT: the Molecular INTeraction database
DOMINO: a database of domain-peptide interactions
RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
The low molecular weight proteome of Halobacterium salinarum.
Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis
Comparative interactomics: comparing apples and pears?
Prediction of Ras-effector interactions using position energy matrices
Structures in systems biology
A genome-wide Ras-effector interaction network
Is proteomics the new genomics?
The E3 ligase Aip4/Itch ubiquitinates and targets ErbB-4 for degradation
WI-PHI: a weighted yeast interactome enriched for direct physical interactions
Motif decomposition of the phosphotyrosine proteome reveals a new N-terminal binding motif for SHIP2
NetPhosYeast: prediction of protein phosphorylation sites in yeast
Locating proteins in the cell using TargetP, SignalP and related tools
Proteomics analysis of Thermoplasma acidophilum with a focus on protein complexes
Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
Live-Cell Imaging of Enzyme-Substrate Interaction Reveals Spatial Regulation
Implementation and application of a versatile clustering tool for tandem mass spectrometry data
Modelling the CheY(D10K,Yl00W) Halobacterium salinarum mutant: sensitivity analysis allows choice of parameter to be modified in the phototaxis model
A la carte proteomics with an emphasis on gel-free techniques
Assessing a novel microfluidic interface for shotgun proteome analyses
Caspase-14 protects against epidermal UVB photodamage and water loss
Large-scale identification of N-terminal peptides in the halophilic archaea Halobacterium salinarum and Natronomonas pharaonis
Combination of COFRADIC and high temperature - extended column length conventional liquid chromatography: A very efficient way to tackle complex protein samples
The transcriptional repressor Glis2 is a novel binding partner for p120 catenin
Stucke VM, Timmerman E, Vandekerckhove J, Gevaert K, Hall A
Proteome-wide identification of HtrA2/Omi substrates
The C-terminus of CIS defines its interaction pattern
Structures in systems biology
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes
A small heat shock protein of Ostertagia ostertagi: stage-specific expression, heat inducibility, and protection trial
Regulation and role of Raf-1/B-Raf heterodimerization.
Regulation of the Raf-MEK-ERK pathway by protein phosphatase
Real-time observation of trigger factor function on translating ribosomes.
Proteome-wide characterization of N-glycosylation events by diagonal chromatography.
Protein processing and other modifications analyzed by diagonal peptide chromatography
PRIDE: a public repository of protein and peptide identifications for the proteomics community
Prediction of protein-protein interaction based on structure
The power of cooperative investigation: summary and comparison of the HUPO Brain Proteome Project pilot study results
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.
Noise in transcription negative feedback loops: simulation and experimental analysis.
A new functional, chemical proteomics technology to identify purine nucleotide binding sites in complex proteomes.
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
Improved tandem mass spectrometric characterization of 3-nitrotyrosine sites in peptides
Identification and characterization of immunogenic proteins of mycoplasma genitalium.
The HUPO Brain Proteome Project jamboree: centralised summary of the pilot studies.
Applications of diagonal chromatography for proteome-wide characterization of protein modifications and activity-based analyses
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells
Functional annotation of proteins identified in human brain during the HUPO Brain Proteome Project pilot study.
DOMINO: a database of domain-peptide interactions.
Differential analysis of Saccharomyces cerevisiae mitochondria by free flow electrophoresis
Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast
A comparison of the HUPO Brain Proteome Project pilot with other proteomics studies.
Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers
Cell_motility: a cross-platform, open source application for the study of cell motion paths.
Archaeal N-terminal protein maturation commonly involves N-terminal acetylation: a large-scale proteomics survey
Regulation of the Raf-MEK-ERK pathway by protein phosphatase 5
GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells
Regulation and role of Raf-1/B-Raf heterodimerization
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
The ubiquitin domain superfold: structure-based sequence alignments and characterization of binding epitopes
Crystal structure of an archaeal actin homolog
The HUPO Brain Proteome Project jamboree: centralised summary of the pilot studies
A complex interaction pattern of CIS and SOCS2 with the leptin receptor
PRIDE: a public repository of protein and peptide identifications for the proteomics community
Improving the reliability and throughput of mass spectrometry-based proteomics by spectrum quality filtering
Cell_motility: a cross-platform, open source application for the study of cell motion paths
When kinases meet mathematics: the systems biology of MAPK signalling
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
The molecular make-up of a tumour: proteomics in cancer research
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
Mammalian sterile 20-like kinases in tumor suppression: an emerging pathway
TOM software toolbox: acquisition and analysis for electron tomography
DBToolkit: processing protein databases for peptide-centric proteomics
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap
A quantitative model of the switch cycle of an archaeal flagellar motor and its sensory control
Proteome-wide analysis of chaperonin-dependent protein folding in Escherichia coli
Recognizing and defining true Ras binding domains I: biochemical analysis
Recognizing and defining true Ras binding domains II: In silico prediction based on homology modelling and energy calculations
5th HUPO BPP Bioinformatics Meeting at the European Bioinformatics Institute in Hinxton, UK--Setting the analysis frame
Data management and preliminary data analysis in the pilot phase of the HUPO Plasma Proteome Project
Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis
Diagonal reverse-phase chromatography applications in peptide-centric proteomics: Ahead of catalogue-omics?
Mechanism of divergent growth factor effects in mesenchymal stem cell differentiation
Comparative interactomics
Recognizing and defining true Ras binding domains II: in silico prediction based on homology modelling and energy calculations
Recognizing and defining true ras binding domains I: biochemical analysis
Phosphotyrosine interactome of the ErbB-receptor kinase family
Modeling and simulation of intracellular dynamics: choosing an appropriate framework
Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
Mass spectrometry for the detection of differentially expressed proteins: a comparison of surface-enhanced laser desorption/ionization and capillary electrophoresis/mass spectrometry
Quantitative profiling of the membrane proteome in a halophilic archaeon.
Oncogenic B-Raf mutations; Crystal clear at last
Integrative analysis of the mitochondrial proteome in yeast
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics
Global differential non-gel proteomics by quantitative and stable labeling of tryptic peptides with oxygen-18
Reversible labeling of cysteine containing peptides allows their chromatographic isolation for non-gel proteome studies
Improved peptide identification in proteomics by two consecutive stages of mass spectromectric fragmentation
Trypsin cleaves exclusively C-terminal to arginine and lysine residues
A novel proteomic screen for Peptide-protein interactions
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Last Changed: 02.08.2004